Process for preparing 2-amino-5-formylthiazole and its hydrobrom

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D27720

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042257190

ABSTRACT:
Process for the preparation of 5-formyl-2-aminothiazole hydrobromide and 2-amino-5-formylthiazole which comprises reacting bromomalonaldehyde and thiourea in the substantial absence of acid or base to form the 5-formyl-2-aminothiazole hydrobromide, and then treating the same with base to form the aminothiazole.

REFERENCES:
patent: 2468401 (1949-04-01), King et al.
patent: 3933838 (1976-01-01), Manghisi

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