Method of oral delivery with an adherent controlled-release salt

Details Method of oral delivery with an adherent controlled-release salt Method of oral delivery with an adherent controlled-release salt

1991-08-30

1992-11-17

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424 49, 424401, 424434, 424435, 424451, 424461, 424463, 424492, 424494, 424496, 424497, A61K 956

Patent

active

051641950

ABSTRACT:
A salt sensitive capsule has been developed which dissolves in the mouth and releases the encapsulated internal ingredient(s). The outer salt sensitive shell maintains its integrity when kept at a preselected aqueous salt concentration. When introduced into the mouth, the degree of salinity is lower and causes the shell to disassociate and release the internal component. The capsules may be associated with an adhesive system so that the capsules are topically applied to mouth tissue. The adhesive system is compatible with maintenance of the salt sensitive shell.

REFERENCES:
patent: 3911099 (1975-10-01), DeFoney et al.
patent: 4462982 (1984-07-01), Samejima et al.
patent: 4889720 (1989-12-01), Konishi
patent: 4983392 (1991-01-01), Robinson

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