Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-01-30
1999-10-05
Hutzell, Paula K.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4353201, 435325, 435348, 4352523, 536 231, 536 235, C12G 168, C12N 120, C12N 1500, C07H 2102
Patent
active
059622326
ABSTRACT:
The invention provides human protein kinase molecules (HPKM) and polynucleotides which identify and encode HPKM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HPKM.
REFERENCES:
Hillier et al. Genbank est database, accession No. H29221, Jul. 1995.
Hanks, S.K. and Hunter, T. "The Eukaryotic Protein Kinase Superfamily" The Protein Kinase Facts Books, Academic Press, San Diego, CA, I:7-20 (1995).
Bairoch, A. et al., "The PROSITE database, its status in 1995" Nucleic Acids Res. (1996) 24:189-196.
Isselbacher, K.J. et al., Harrison's Principles of Internal Medicine (1994) McGraw-Hill, New York, NY, pp. 416-431, 1887.
Haribabu, B., et al., "Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase", The EMBO Journal, (1995) 14:3679-3686.
Gao, G. et al., "Non-Catalytic .beta.- and .gamma.-Subunit Isoforms of the 5'-AMP-activated Protein Kinase" J. Biol. Chem. (1996) 271:8675-8681.
Egan, S.E. and Weinberg, R.A., "The pathway to signal achievement," Nature (1993) 365:781-783.
Li, B. et al., "prk, a Cytokine-inducible Human Protein Serine/Threonine Kinase Whose Expression Appears to be Down-regulated in Lung Carcinomas" J. Biol. Chem. (1996) 271:19402-19408.
Charbonneau, H. and Tonks, N.K., "1002 Protein Phosphatases?," Annu.Rev.Cell Biol., (1992) 8:463-93.
Akerblom Ingrid E.
Bandman Olga
Corley Neil C.
Guegler Karl J.
Hillman Jennifer L.
Hutzell Paula K.
Incyte Pharmaceuticals Inc.
Sun-Hoffman Lin
LandOfFree
Protein kinase molecules does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Protein kinase molecules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein kinase molecules will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1170054