Systematic evolution of ligands by exponential enrichment: chemi

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, 536 2431, 536 254, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2102, C07H 2104

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active

059622199

ABSTRACT:
This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.

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