Pharmaceutical formulation with effervescent couple

Details Pharmaceutical formulation with effervescent couple Pharmaceutical formulation with effervescent couple

1994-11-30

1999-10-05

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424441, A61K 946

Patent

active

059620226

ABSTRACT:
A chewable tablet comprises a medicament dispersed in a chewable base, such as mannitol, together with an effervescent couple, such as citric acid-sodium bicarbonate. The combination of effervescence and chewability with optional flavorings improves the taste characteristics of the medicament in oral administration. A disintegrant such as microcrystalline cellulose may be added to give the patient the option of dispersing the tablet in water.

REFERENCES:
patent: 4639368 (1987-01-01), Niazi et al.
patent: 4952402 (1990-08-01), Sparks et al.
patent: 5178878 (1993-01-01), Wehling et al.

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