Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-06-30
1990-02-13
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31415
Patent
active
049007416
ABSTRACT:
An orally administered pharmaceutical composition for treating peptic ulcers and other gastrointestinal conditions associated with hyperacidity, which includes both the H.sub.2 -receptor antagonist cimetidine and the antimuscarinic agent pirenzepine.
REFERENCES:
Chem. Abst. (1985)-153135t, vol. 103.
Chem. Abst. (1982)-621K, vol. 96.
Chem. Abst. (1981)-18425p, vol. 95.
Complete Inhibition of Food-Stimulated Gastric Acid Secretion by Combined Application of Pirenzepine and Rainitidine, Gut, 1981, 22, 542-548, Londong, et al.
Simple Approach to Assess Potentiated Drug Combinations in Clinical Trials: Studies With Pirenzepine Plus H.sub.2 -Receptor Antagonists, International Journal of Clinical Pharmacology, Therapy and Toxicology, vol. 23, No. 6-1985, (pp. 283-287).
Interactions of Cimetidine and Pirenzepine on Peptone-Stimulated Gastric Acid Secretion in Man, Scand. J. Gastroenterol., Suppl., 15 (66), pp. 103-112 (1980), Londong et al.
BioMed Researchy Consultants, Ltd.
Friedman Stanley J.
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