N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical composit

Details N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical composit N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical composit

1988-10-07

1990-02-13

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514321, 546198, 546199, A61K 3138, A61K 3139, A61K 31435, C07D41712

Patent

active

049007386

ABSTRACT:
N-heterocyclic-4-piperidiyl-amides as analgesics and antagonists of opioids with respect to such undesirable side effects as respiratory depression.
Exemplary compounds have the formula ##STR1## in which formula R is a heterocyclic group, and R.sup.1 is a furanyl, thienyl, or lower alkoxy lower alkyl group, and R.sup.2 is a lower alkyl phenyl group.

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