Method of making (3-amino-1H-pyrazol-4-yl) (aryl)methanones

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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546279, 548362, 548374, 548375, 548377, C07D40106, C07D40506

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active

049804723

ABSTRACT:
(3-Amino-1H-pyrazol-4-yl)(aryl)methanones which are new compounds having utility as intermediates for the preparation of aryl and heteroaryl-[7-(aryl and heteroaryl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones, which are therapeutic agents.

REFERENCES:
patent: 3660425 (1972-05-01), DeWald et al.
Butler and DeWald, "New General Methods . . . ", J. Org. Chem., 1971, 36, pp. 2542-2547.
Butler, Wise and DeWald, "(1,3-Dialkyl-5-amino-1H-pyrazol-4-yl)aryl-methanones", J. Med. Chem., 1984, 27, pp. 1346-1400.

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