Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-06-07
1998-04-07
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 72, 435 723, 436 63, 436 64, 436813, G01N 3353
Patent
active
057363404
ABSTRACT:
A purified glycoprotein complex of over 1200 kD apparent native molecular weight having a sedimentation value of approximately 25S and having the ability to selectively bind human Mac-2 or interfere with PHA activation of lymphocytes, DNA sequences that encode the protein, and expression systems for expressing it, thus providing for reagents that are useful for treating or diagnosing diseases, including cancer, infectious disease, and diseases of the immune system, and for monitoring the concentration of the glycoprotein in human milk.
REFERENCES:
Linsley, et al., Biochemistry, vol. 25, pp. 2978-2986, 1986.
Inohara, et al., Biochem Biophys Res Commun, vol. 201, No. 3, pp. 1366-1375, 1994.
Casipit Clayton L.
Halenbeck Robert F.
Koths Kirston E.
Taylor Eric W.
Wang Alice M.
Blackburn Robert P.
Chiron Corporation
Savereide Paul B.
Scheiner Toni R.
Simboli Paul B.
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