Chlorhexidine complex

Details Chlorhexidine complex Chlorhexidine complex

1989-04-27

1990-12-25

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Dentifrices

536 3, 424 78, 514 54, 514779, 514901, 514781, A61K 716

Patent

active

049801503

ABSTRACT:
A chlorhexidine complex is prepared by complexing chlorhexidine (a divalent, cationic antiseptic) with an anionic polymer such as algin or carboxymethylcellulose. The complex is insoluble but can be granulated or crushed to a fine powder. In powdered form the complex forms stable aqueous dispersions. The chlorhexidine complex is suitable for inclusion in oral hygiene compositions such as dentrifrices, and in other antibacterial compositions such as opthalmic under-eye-lid treatment capsules topical preparations and ocular solutions.

REFERENCES:
patent: 3842168 (1974-10-01), Colodney
patent: 3956480 (1976-05-01), Dichter et al.
patent: 4289749 (1981-09-01), Keith et al.
patent: 4393219 (1983-07-01), Inoue et al.
patent: 4569837 (1986-02-01), Suzuki et al.
patent: 4666896 (1987-05-01), Walter, Jr. et al.
patent: 4857303 (1989-08-01), Grollier
patent: 4877617 (1989-10-01), Namikoshi et al.

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