Dibenzoxazepine N-carboxylic acid hydrazides and derivatives

Details Dibenzoxazepine N-carboxylic acid hydrazides and derivatives Dibenzoxazepine N-carboxylic acid hydrazides and derivatives

1973-02-05

1976-11-02

Milestone, Norma S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424244, C07D26720

Patent

active

039897192

ABSTRACT:
Derivatives of the dibenzoxazepine N-carboxylic acid hydrazides are acylated to yield N,N'-diacyl hydrazines which are useful pharmacological agents as is evidenced by their acetylcholine antagonist, prostaglandin antagonist, and 5-hydroxytryptamine antagonist activity.

REFERENCES:
patent: 3534019 (1970-10-01), Coyne et al.
William E. Coyne et al., Jour. Med. Chem., 11 (6), (1968), pp. 1158-1160.
J. H. Sanner, Arch. int. Pharmacodyn., July 1969, No. 1, pp. 46-56.

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