Soft quaternary surface active agents exhibiting antibacterial a

Details Soft quaternary surface active agents exhibiting antibacterial a Soft quaternary surface active agents exhibiting antibacterial a

1975-09-22

1976-11-02

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602395, 26029353, 260295R, 2602955R, 2602955A, 2603971, 260404, 2604045, 260469, 260473A, 260473R, 260482R, 424263, 424267, 424273, 424312, C07D23360

Patent

active

039897117

ABSTRACT:
Soft quaternary surface active agents having the formula: ##EQU1## wherein ##EQU2## represents a tertiary open chain or cyclic aliphatic amine; wherein ##EQU3## represents an aromatic amine; wherein R represents a member selected from the group consisting of a hydrogen atom, a C.sub.1 -C.sub.20 open chain or cyclo alkyl group, a C.sub.1 -C.sub.20 alkoxyalkyl group, a C.sub.1 -C.sub.20 acyloxyalkyl group, a C.sub.1 -C.sub.20 haloalkyl group, a C.sub.1 -C.sub.20 carboxyalkyl group, an aryl group, and a substituted aryl group, whose substituents are selected from the group consisting of a halogen atom, an O--C.sub.1 -C.sub.4 alkyl group, an O--C.sub.1 -C.sub.8 acyl group a nitro group, a carboxyl group, and a carboethoxy group; wherein R.sub.1 represents a C.sub.9 -C.sub.22 straight or branched alkyl group, a ##EQU4## group, wherein R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are each selected from the group consisting of a hydrogen atom, a methyl group or an ethyl group, a C.sub.0 -C.sub.22 straight or branched ##SPC1##
Group, wherein n in each occurrence and m represent an integer of from 0 to 22, an ##SPC2##
Group, wherein A represents a C.sub.0 -C.sub.22 straight or branched alkyl group as above or a -(CH.sub.2 CH.sub.2 O).sub.p group, wherein the p represents an integer of from 0 to 22, and the residue of any naturally occurring bile acid or synthetic derivative thereof; and wherein X represents a halogen atom or any other organic or inorganic movement anion are disclosed.
All compounds encompassed within the above-described generic formulae find use as "soft" antibacterial agents of extremely low toxicity.

REFERENCES:
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patent: 2493319 (1950-01-01), Shonle et al.
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Guibe-Jampel et al. Chem. Abst. 1973, vol. 79, No. 31982g.
Grabowski et al. Chem. Abst. 1974, vol. 81, No. 114877u.

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