Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1984-01-23
1986-11-25
Marantz, Sidney
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
4351722, 435240, 435241, 435284, 435948, 530351, 935106, 935109, C12P 2100, C12N 1500, C12N 500, C12N 502
Patent
active
046249176
ABSTRACT:
The present invention relates to a process for the production of human T-cell growth factor (abbreviated as "hTCGF" hereinafter). More precisely, the present invention relates to an improved process for the mass-production of hTCGF, comprising transplanting human cells capable of producing hTCGF to a non-human warm-blooded animal, multiplying said cells while allowing the cells to receive the nutrient body fluid supplied from the animal, and producing hTCGF in the multiplied human cells. By the practice of the present invention, a much larger amount of hTCGF, i.e., about 2-10-fold or more larger than that obtained by conventional processes, can be easily obtained; thus, hTCGF in an amount sufficient to carry out various clinical treatments can be easily provided by the present invention.
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DeSantis Patricia L.
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
Marantz Sidney
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