Piperidinyl and piperazinyl derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514317, 514318, 514327, 514330, 514252, 544360, 544366, 544370, 544383, 546194, 546210, 546216, 546225, 546236, 546240, A61K 31445, C07D21120, C07D21130, C07D40112

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active

052023460

ABSTRACT:
Compounds of the formula: ##STR1## in which R.sup.1 is alkylsulfonamido of 1 to 6 carbon atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO.sub.2,--CN, 1-imidazolyl or 1,2,4-triazol-1-yl;

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patent: 4920116 (1990-04-01), Morgan, Jr. et al.
patent: 4996215 (1991-02-01), Oinuma et al.
Bexton et al., Pharmac. Ther., 17, 315-55 (1982).
Vaughan-Williams, J. Clin. Pharmacol., 24, 129-47 (1984).
Steinberg et al., Ann. Rep. Med. Chem., 21, 95-108 (1986).
Oinuma et al., J. Med. Chem., 33, 903 (1990).
Morgan et al., J. Med. Chem., 33, 2883 (1990).

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