Tetracyclic triterpene derivatives with immunosuppressant activi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549268, 549354, 549 60, 5462817, 514337, 514444, A61K 31365, C07D31306

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active

061002933

ABSTRACT:
The compounds of Formula I ##STR1## are useful as immunosuppressive agents.

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Abreu, et al., "A Nor-Triterpenoid From Lophanthera Lactescens", Phytochemistry, vol. 29(7), pp. 2257-2261, 1990.
Sabata, et al., "Tetranortriterpenoids and Related Substances. Part 19.1 Revised Structures od Atalantolide and Atalantin, Limonoids from the Root Bark of Atalantia Monophylla Correa (Rutaceae)", J. Chem. Soc. Perkin I, pp. 1876-1877, 1977.

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