Recombinant cell clone having increased stability in serum- and

Details Recombinant cell clone having increased stability in serum- and Recombinant cell clone having increased stability in serum- and

1998-06-19

2000-08-08

Guzo, David

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 696, 435455, 435325, 435352, 435358, 435383, 435395, 435404, C12P 2102, C12N 510

Patent

active

061000612

ABSTRACT:
Disclosed are a stable recombinant cell clone which is stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.

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