Process for the production of N,N'-bis-(3-aminophenyl)-ureas

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564 48, C07C27318

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049946110

ABSTRACT:
The present invention is directed to a process for the preparation of N,N'-bis-(3-aminophenyl)-ureas corresponding to formula (I) ##STR1## wherein R represents a linear or branched C.sub.1 -C.sub.6 alkyl group which is in the 2-, 4- and/or 6-position,
characterized in that the corresponding phenylene diamines are reacted with urea in a molar ratio of greater than 2:1 in chlorobenzene as solvent.

REFERENCES:
patent: 1617847 (1927-02-01), Heinze
patent: 2503797 (1950-04-01), Brunner et al.
patent: 3214468 (1965-10-01), Frick et al.
I. L. Khmel'nitskaya et al. en Zhurnal Obschei Khimii 30 (2), 1960.
W. R. Turner & L. M. Werbel in J. Med. Chem. 28, 1985.
A. Ostrogovich in Liebigs Ann; 293 1896, on pgs.
DRP 140613, Vom. 4, Dec. 1900 ab.
DRP 268658, Vom. 14, Sep. 1912.

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