Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1989-11-14
1991-02-19
Hollrah, Glennon H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
564 48, C07C27318
Patent
active
049946110
ABSTRACT:
The present invention is directed to a process for the preparation of N,N'-bis-(3-aminophenyl)-ureas corresponding to formula (I) ##STR1## wherein R represents a linear or branched C.sub.1 -C.sub.6 alkyl group which is in the 2-, 4- and/or 6-position,
characterized in that the corresponding phenylene diamines are reacted with urea in a molar ratio of greater than 2:1 in chlorobenzene as solvent.
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patent: 3214468 (1965-10-01), Frick et al.
I. L. Khmel'nitskaya et al. en Zhurnal Obschei Khimii 30 (2), 1960.
W. R. Turner & L. M. Werbel in J. Med. Chem. 28, 1985.
A. Ostrogovich in Liebigs Ann; 293 1896, on pgs.
DRP 140613, Vom. 4, Dec. 1900 ab.
DRP 268658, Vom. 14, Sep. 1912.
Grogler Gerhard
Kopp Richard
Ruckes Andreas
Bayer Aktiengesellschaft
Gil Joseph C.
Hollrah Glennon H.
Roy Thomas W.
Treanor Susan P.
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