Process for the preparation of hydrocortisone

Details Process for the preparation of hydrocortisone Process for the preparation of hydrocortisone

1992-08-25

1993-11-09

Cintins, Marianne M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

552569, C07J 500

Patent

active

052604632

ABSTRACT:
An improved process for the preparation of hydrocortisone and novel intermediates which avoids an 11-hydroxylation step and results in improved yields.

REFERENCES:
Venton, et al., J of Med. Chem. vol. 18(1), 1975; 9-16.
Karmas, George, J Org. Chem. vol. 33(6), 1968; 2436-2440.

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