Thienobenzoxepins and naphthothiophenes

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514422, 546213, 548527, A61K 31445, C07D40906

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active

052603199

ABSTRACT:
Novel thienobenzoxepins and naphthothiophenes, intermediates and processes for the preparation thereof, and methods of alleviating pain utilizing compounds or compositions thereof are disclosed.

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J. T. Strupczewski, et al., Journal of Medicinal Chemistry, 28, 761 (1985) published in the U.S. and entitled "Synthesis and Neuroleptic Activity of 3-(1-Substituted-4-piperidinyl)-1,2-benzisoxazoles".
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K. Thomae, Chemical Abstracts, 64, 19575 (1966) published in the U.S. and entitled "5,6-Dihydromorphanthridines".
C. W. Thornber, "Isosterism and Molecular Modification in Drug Design", Chemical Society Reviews, 8,563 to 565 (1979), published in the United Kingdom.

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