Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat sk

Details Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat sk Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat sk

1994-12-21

1996-12-31

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514309, A61K 3147

Patent

active

055894836

ABSTRACT:
Inhibition of the enzyme poly (ADP-ribose) polymerase can delay the onset of senescence and inhibitors of the enzyme can be used to treat diseases caused or exacerbated by cellular senescence.

REFERENCES:
patent: 5032617 (1991-07-01), Lee et al.
patent: 5041653 (1991-08-01), Lee et al.
patent: 5215738 (1993-06-01), Lee et al.
patent: 5272057 (1993-12-01), Smulson et al.

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