2-aminomethyl-chromans

Details 2-aminomethyl-chromans 2-aminomethyl-chromans

1994-03-22

1995-11-21

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31174

Patent

active

054688825

ABSTRACT:
Aminomethyl-chromans are obtained by alkylation of correspondingly substituted amines or by reductive amination of correspondingly substituted aldehydes. The aminomethyl-chromans can be used as active compounds in medicaments, in particular for the treatment of diseases of the central nervous system.

REFERENCES:
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patent: 5137901 (1992-08-01), Junge et al.
Ram Pratap, Indian Journal of Chemistry, 11 May 1981, pub. Dec. 1981, pp. 1063-1067.
W. U. Dompert, Naunyn-Schmiedeberg's Arch Pharmacol, 1985, pp. 467-470.
Eckard Weber, Proc. Natl. Acad. Sci. USA, vol. 83, Nov. 1986, pp. 8784-8788.
Michael P. Kavanaugh, Proc. Natl. Acad. Sci., Apr. 1988, pp. 2844-2848.
W. Clark Still, J. Org. Chem., 1978, pp. 2923-2927.

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