Resolution of 2-benzyl-4-piperidone-succinic acid

Details Resolution of 2-benzyl-4-piperidone-succinic acid Resolution of 2-benzyl-4-piperidone-succinic acid

1992-07-01

1994-01-18

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21122

Patent

active

052801225

ABSTRACT:
This invention relates to a process for resolving racemic or optically enriched 2-benzyl-4-piperidone-succinic acid, comprising reacting such compound with (+)-cis-N-benzyl-2-(hydroxymethyl)-cyclohexylamine, (-)-cis-N-benzyl-2-(hydroxymethyl)-cyclohexylamine or (+)-dehydroabietylamine.

REFERENCES:
patent: 4845272 (1989-07-01), Nohira et al.
Harada et al., J. Org. Chem, 55, 1679-1682 (1990).

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