Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-12-21
1995-05-02
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514328, A61K 31445
Patent
active
054119707
ABSTRACT:
A method of inhibiting lentivirus is disclosed which comprises mammalian host susceptible to said lentivirus with a virally inhibitory effective amount of an O-acylated derivative of 1,5-dideoxy-1,5-imino-D-glucitol and their N-alkyl, N-acyl and N-aroyl derivatives in which from one to four of the free hydroxyl groups are O-acylated with carboxylic alkanoyl radicals selected from the group consisting of .omega.,.omega.,.omega.-trifluoroalkanoyl having from three to eight carbon atoms, carboxylic cycloalkanoyl groups having from four to eight carbon atoms and carboxylic acyclic alkanoyl groups having from two to ten carbon atoms, wherein the N-aroyl groups contain from 7 to 14 carbon atoms, the N-acyl groups contain from 4 to 8 carbon atoms and the N-alkyl groups contain from 1 to 14 carbon atoms.
REFERENCES:
patent: 4182767 (1980-01-01), Murai et al.
patent: 4348402 (1982-09-01), Kinast et al.
patent: 4639436 (1987-01-01), Junge et al.
patent: 4849430 (1989-07-01), Fleet et al.
patent: 5003072 (1991-03-01), Partis et al.
Frank et al., Antimicrob. Agents Chemother. 31, 1369-1374 (1978).
Sunkara et al., Soc. Complex Carbohyd. 17th Ann. Meet., San Antonio, Nov. 3-5, 1988, Abst. 9.
Chem. Abst. 86, 167851r (1987).
Chem. Abst. 68, 78526Z (1968).
Chem. Abst. 67, 3207s (1967).
Chem. Abst. 92, 7688m (1980).
Chem. Abst. 84, 44569F (1976).
Koszyk Francis J.
Mueller Richard A.
Partis Richard A.
Cebulak Mary C.
G. D. Searle & Co.
Meyer Scott J.
Raymond Richard L.
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