Use of delta opioid receptor antagonists to treat cocaine abuse

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 3144

Patent

active

054119650

ABSTRACT:
A therapeutic method is provided to inhibit the use of cocaine by the administration of an effective amount of certain selective delta opioid receptor antagonists to a human patient in need of such treatment.

REFERENCES:
patent: 4816586 (1989-03-01), Portoghese et al.
Bain et al., Life Sciences, 40, 1119 (1983).
Beach, Can J. Psychol., 11, 104 (1957).
Belluzi et al., Nature, 266, 556 (1977).
Bilsky et al., Life Sciences, 50, PL-85 (1992).
Bilsky et al., Pharmacol. Biochem. Behav., 37, 425 (1990).
Carr et al., The Neuropharmacological Basis of Reward, S. Leibman et al., eds., Oxford U. Press, N.Y., (1989).
Carroll et al., J. Med. Chem., 35, 969 (1992).
Clark et al., J. Med. Chem., 16, 1620 (1973).
Clouet et al., eds., "Mechanisms of Cocaine Abuse and Toxicity", NIDA Research Monograph (1988).
Cotton et al., Eur. J. Pharmacol., 97, 331 (1984).
Drower et al., J. Pharmacol. Exp. Ther., 259, 725 (1991).
Froehlich et al., Alcoholism Clin. and Exp. Res. Abstract 20, p. 315 (1991).
Garcia et al., Brit J. Radiology, 30, 318 (1957).
Gawin et al., Arch. Gen Psychiatry, 43, 107 (1986).
Glennon, Psychopharmocology: The Third Generation of Progress, H. Y. Meltzer, ed., Raven Press, N.Y. (1987).
Griffiths et al., in Advances in Substance Abuse, vol. 1, N. K. Mello, ed., UAI Press Inc., Greenwich, Conn. (1980).
Johanson et al., Pharmacol. Rev., 41, 3 (1989).
Kozikowski et al., Med. Chem. Res., 1, 312 (1991).
Martin, Pharmacol. Rev., 35, 283 (1983).
Menkens et al., Eur. J. Pharmacol., 219, 345 (1992).
Mucha et al., Brain Res., 243, 91 (1982).
Musto, Sci. Amer., 256, 40 (1991).
Portoghese et al., J. Med. Chem., 31, 281 (1988).
Portoghese et al., J. Med. Chem., 33, 1547 (1990).
Portoghese et al., Eur. J. Pharmacol., 146, 185 (1988).
Portoghese et al., J. Pharmacol. Exp. Ther., 258, 299 (1991).
Reid et al., Life Sciences, 52, 67 (1993).
Reid, Methods of Assessing the Reinforcing Properties of Abused Drugs, M. A. Bozarth, ed., Springer-Verlag, N.Y. (1987).
Reid et al., Physiol. Psychol. 4, 269 (1976).
Shaw et al., Life Sci., 31, 1259 (1982).
Sofuoglu et al., J. Pharmacol. Exp. Ther., 257, 676 (1991).
Spanagel et al., J. Neurochem., 55, 1734 (1990).
Stapleton et al., Physiol. Psychol., 7, 427 (1979).
Ukai et al., Eur. J. Pharm., 231, 143 (1993).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of delta opioid receptor antagonists to treat cocaine abuse does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of delta opioid receptor antagonists to treat cocaine abuse, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of delta opioid receptor antagonists to treat cocaine abuse will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1137244

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.