Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Urogenital system
Patent
1994-01-07
1995-05-02
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Urogenital system
424643, A61K 3330, A61K 3548
Patent
active
054117488
ABSTRACT:
A composition of matter comprising zinc and an extract of animal prostatic tissue provides a convenient source of both fatty acids and zinc for dietary and therapeutic purposes. The pharmaceutical composition is useful for the treatment of diabetes. 05411748821 00000000000000000465034000000000000000000000000000000000000000000000000000 000098
REFERENCES:
patent: 4302447 (1981-11-01), Horrobin
Buxade Vinas, Chem. Abstracts CA107(5):39206z, 1985.
Buxade Vinas, Chem. Abstracts CA107(5):39205y, 1985.
Rossetti et al., Chem. Abstracts CA114(9):75015q, 1990.
Micossi et al., Chem. Abstracts CA91(11):83900w, 1978.
M. K. Song, et al.; Journal of Nutrition; vol. 109, No. 12, Dec. 1979; pp. 2152-2158; "Evidence for an Important Role of Prostaglandins E.sub.2 and F.sub.2 in the Regulation of Zinc Transport in the Rat".
Moon K. Song, et al.; Comp. Biochem. Physiol., vol. 101A, No. 3, pp. 477-481, 1992; "Prostaglandin Interacts with Steroid Sex Hormones in the Regulation of Intestinal Zinc Transport".
M. K. Song, et al.; Life Sciences, vol. 33, pp. 2399-2408; "A New Low-Molecular-Weight Calcium-Binding Ligand in Rat Small Intestine", 1983.
N. F. Adham, et al.; Nutrition and Metabolism; vol. 24: 281-290 (1980); "Effect of Calcium and Copper on Zinc Absorption in the Rat".
Moon K. Song, et al.; Comp. Biochem. Physiol.; vol. 85C, No. 2, pp. 283-289; 1986; "Relative Zinc-Binding Activities of Ligand in the Cytosol of Rat Small Intestine".
Moon K. Song; Comp. Biochem. Physiol.; vol. 87A, No. 2, pp. 223-230, 1987; "Low-Molecular-Weight Zinc-Binding Ligand: A Regulatory Modulator for Intestinal Zinc Transport".
Moon K. Song, et al.; Biological Trace Element Research; vol. 11, 1986; pp. 75-88; "Levels and Distribution of Zinc, Copper, Magnesium, and Calcium in Rats Fed Different Levels of Dietary Zinc".
M. K. Song., et al.; Biochemical Archives, vol. 1, pp. 75-83; "Metabolic Influences on Intestinal Zinc Uptake in Rats", 1985.
Moon K. Song, et al.; Biological Trace Element Research; vol. 6, 1984; "Metabolism of Zinc-Binding Ligands in Rat Small Intestine", pp. 181-193.
George Y. Luh, et al.; Comp. Biochem. Physiol.; vol. 91B, No. 3, pp. 569-576, 1988; "Characterization of the Low Mol. Wt Zinc-Binding Ligand From Rat Small Intestine by Comparison to the Organic Zinc-Binding Ligands".
S. Arver; Acta Physiol Scand 1982, 116:67-73; "Zinc and zinc ligands in human seminal plasma".
M. Schneir, et al.; Diabetes, vol. 31, May 1982; "Streptozotocin-induced Diabetic Rat Enhanced Catabolism of collagen Formed Both Before and During the Diabetic State".
M. Johnson, et al.; The Lancet I: 325-326, 1979; "Vascular Prostacyclin May be Reduced in Diabetes in Man".
K. Engelbart, et al.; Virchows Arch.Abt.B.Zellpath. 4, 294-302 (1970); "Uber das funktionelle Verhalten von Zink und Insulin in den B-Zellen des Rattenpankreas".
J. L. Marx; Science, vol. 225, pp. 1381-1383; Sep. 1984; "Diabetes--A Possible Autoimmune Disease".
L. Hurley, et al.; The Lancet I: 1979; pp. 677-678; "Zinc Citrate, Human Milk and Acrodermatitis Enteropathica".
S. Katayama, et al.; Hypertension Program Unit, vol. 7, No. 4, Jul.-Aug. 1985; pp. 554-561; "Hypertension in Experimental Diabetes Mellitus Renin-Prostaglandin Interaction".
W. T. Johnson, et al.; J. Nutr. 115: 1217-1227, 1985; "Intestinal Absorption and Excretion of Zinc in Streptozotocin-Diabetic Rats as Affected by Dietary Zinc and Protein".
R. P. Robertson, et al.; Journal of Clinical Investigation, vol. 60, Sep. 1977; pp. 747-753; "A Role for Prostaglandin E in Defective Insulin Secretion and Carbohydate Intolerance in Diabetes Mellitus".
G. W. Evans, et al; J.Nutr. 110:1076-1080, 1980; "Zinc Absorption in Rats Fed a Low-Protein Diet and a Low-Protein Diet Supplemented with Tryptophan or Picolinic Acid".
H. E. Harrison, et al.; Life Sciences, vol. 23, pp. 351-356; "Decreased Vascular Prostacyclin in Experimental Diabetes", 1978.
M. K. Chooi, et al.; Nutr.Metabol.20: 135-142 (1976); "Influence of Age and Sex on Plasma Zinc Levels in Normal and Diabetic Individuals".
Biochemical Medicine 23, pp. 231-235; 1980; Short Communications; "Altered Synthesis of Prostaglandins in Platelet and Aorta from Spontaneously Diabetic Wistar Rats".
R. J. Illman, et al.; Atherosclerosis, 59, 1986, pp. 313-321; "Time-Course of Changes in Plasma Lipids in Diabetic Rats Fed Diets High in Fish or Safflower Oils".
A. Reznikvo, et al.; Endocrinologia Experimentalis, vol. 24, 1990; pp. 437-447; "Nonsteroid Antiandrogen Inhibiting Effect on Testosterone Metabolism in Rat Prostate and Liver".
H. E. Harrison, et al.; Diabetologia, 18, pp. 65-68, 1980; "Effect of Insulin Treatment on Prostacyclin in Experimental Diabetes".
G. F. Bottazzo, et al.; Immunology Today, vol. 5, No. 8, 1984, pp. 203-231; "Hypotheses on Genetic Contributions to the Aetiology of Diabetes Mellitus".
D. A. Scott, et al.; Connaught Laboratories, University of Toronto, Toronto, Canada; pp. 725-728; "The Insulin and The Zinc Content of Normal and Diabetic Pancrease", 1938.
B. Koletzko, et al.; Eur.J.Pediatr (1985) 143: 310-314; "Fatty acid composition of plasma lipids in acrodermatitis enteropathica before and after zinc supplementation".
F. K. Ghishan, et al.; Life Sciences, vol. 32, pp. 1735-1741; "Intestinal Transport of Zinc in the Diabetic Rat", 1983.
W. B. Kinlaw, M.D., et al.; The American Journal of Medicine, vol. 75, Aug. 1983, pp. 273-277; "Abnormal Zinc Metabolism in Type II Diabetes Mellitus".
Moon K. Song, Ph.D., et al.; The American Journal of Clinical Nutrition 41; Jun. 1985; pp. 1201-1209; "Relationship between zinc and prostaglandin metabolisms in plasma and small intestine or rats".
M. K. Song, et al.; Life Sciences, vol. 42, pp. 687-695; "Intestinal Zinc Transport: Influence of Streptozotocin-Induced Diabetes, Insulin and Arachidonic Acid", 1988.
R. Paul Robertson, M.D.; Symposium on Prostaglandins; Medical Clinic of North American, vol. 65, No. 4, Jul. 1981; "Prostaglandins, Glucose Homeostasis, and Diabetes Mellitus".
M. K. Song, et al.; Prostaglandins Leukotrienes and Medicine 17: 159-166, 1985; "Effect of Oral Administration on Arachidonic Acid on Prostaglandin and Zinc Metabolism in Plasma and Small Intestine of the Rat".
T. Pham et al., "Factors Affecting Zinc Flux Rates of Rat Intestinal Segments Mounted in Ussing Chambers," Biochem. Arch. 7:213-219 (1991).
C. K. Lardinois & G. H. Starich, "Polyunsaturated Fats Enhance Peripheral Glucose Utilization in Rats," J. Am. Coll. Nutr. 10:340-345 (1991).
S. Southon et al., "Hexose Transport and Musocal Morphology in the Small Intestine of the Zinc-Deficient Rat," Br. J. Nutr. 52:371-380 (1984).
M. Song & N. F. Adham, "Role of Prostaglandin E.sub.2 in Zinc Absorption in the Rat," Am. J. Physiol. 234:E99-105 (1978).
M. K. Song et al., "Evidence for a Role of Prostaglandins in the Regulation of Intestinal Zinc Transport," Nutr. Rep. Int'l. 32:71-83 (1985).
D. W. Watkins et al., "Zinc Inhibition of Glucose Uptake in Brush Border Membrane Vesciles from Pig Small Intestine," Pflugers Arch. 415:165-171 (1989).
M. K. Song et al., "Influence of Prostaglandins on Unidirectional Zinc Fluxes Across the Small Intestine of the Rat," Br. J. Nutr. 59:417-428 (1988).
Cintins Marianne M.
Jarvis William R. A.
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