Quinoline quinones and anti-asthmatic use thereof

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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Details

42424857, 544128, 546159, A61K 31505, A61K 3147, C07D21524, C07D40104

Patent

active

044927045

ABSTRACT:
This invention relates to a class of quinoline quinones, which are useful for the therapy of immediate hypersensitivity reactions, such as asthma, and in treating any condition characterized by excessive release of leukotrienes. This invention also includes a method for treating these conditions, which comprises administering to animals, including humans, an effective dose of the quinoline quinone compounds. A further part of this invention is pharmaceutical formulations containing these pharmacologically-active compounds.

REFERENCES:
Long et al., J. Chem. Soc., 3919-3924 (1953).
Petrow et al., J. Chem. Soc., 570-574 (1954).
Pratt, Y. T., J. Org. Chem., 27, 3905-3910 (1962).
Pratt et al., J. Amer. Chem. Soc., 77, 37-40 (1955).
Pratt et al., J. Amer. Chem. Soc., 82, 1155-1161 (1960).

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