Structured orthoester and orthocarbonate drug delivery devices

Details Structured orthoester and orthocarbonate drug delivery devices Structured orthoester and orthocarbonate drug delivery devices

1978-03-02

1978-12-26

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

71DIG1, 71 64F, 128260, 128130, 252316, 424 14, 424 16, 424 19, 424 20, 424 21, 424 28, 424 32, 424 78, A61K 922, A61K 924, A61K 926, A61K 932

Patent

active

041316487

ABSTRACT:
The invention concerns orthoester and orthocarbonate polymers having a repeating mer comprising a hydrocarbon radical and a symmetrical dioxycarbon unit of the general formula: ##STR1## WHEREIN R.sub.1 is a multivalent hydrocarbon radical, R.sub.2 and R.sub.3 are hydrocarbon radicals with at least one of R.sub.2 or R.sub.3 bonded to the dioxycarbon through an oxygen linkage, and which polymers are synthesized by reacting a polyol with an orthoester or orthocarbonate. The polymers are useful for making articles of manufacture, including devices and coatings for delivering beneficial agents.

REFERENCES:
patent: 4001388 (1977-01-01), Shell
patent: 4093709 (1978-06-01), Choi et al.

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