Antihypercholesterolemic compounds

Details Antihypercholesterolemic compounds Antihypercholesterolemic compounds

1989-07-17

1990-06-26

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514460, 514470, 560 9, 560 56, 560107, 562496, A61K 31365, C07D30930

Patent

active

049372637

ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.

REFERENCES:
patent: 3231469 (1966-01-01), Canonica
patent: 4198510 (1980-04-01), Shioiri et al.
patent: 4444784 (1984-04-01), Hoffman et al.

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