Thienotriazolodiazepine compounds and pharmaceutical uses thereo

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514220, 540524, 540565, C07D41312, C07D41712, A61K 3142, A61K 31425

Patent

active

049372408

ABSTRACT:
A thienotriazolodiazepine compound of the formula: ##STR1## wherein each symbol is as defined in the specification or a pharmaceutically acceptable salt thereof, and pharmaceutical uses thereof.
Said compounds exhibit PAF-antagonistic activity and are useful for the prevention or treatment of various PAF-induced diseases.

REFERENCES:
patent: 4621083 (1988-11-01), Casels-Stenzel et al.
Weber et al., Chemical Abstracts, vol. 106, 1987, 156502h.
Stransky et al., Chemical Abstracts, vol. 107, 1987, 198366t.
Casels-Stanzel et al., J. of Pharmacology and Experimental Therapeutics, vol. 24, 3, 1987, 974 to 981.
Japanese Journal of Pharmacology, vol. 44, pp. 381-391.

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