Biodegradable organic polymer delivery system for bone morphogen

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Processes of preparing a desired or intentional composition...

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524 17, 523115, 514 21, 424 78, 604891, 623 16, A61K 3702, A61K 3532, C07G 700

Patent

active

045634890

ABSTRACT:
Disclosed is a biodegradable polylactic acid polymer delivery system for delivery of bone morphogenic protein (BMP) to induce formation of new bone in viable tissue. The delivery composition is substantially pure BMP in combination with a biodegradable polylactic acid polymer and it is prepared by admixing the BMP with the biodegradable polymer. The composition is implanted in viable tissue where the BMP is slowly released and induces formation of new bone.

REFERENCES:
patent: 4394370 (1983-07-01), Jefferies
patent: 4428082 (1984-01-01), Naficy
patent: 4430760 (1984-02-01), Smestad

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