Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1998-05-06
1999-08-10
Bawa, Raj
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424 45, 424 49, 424 52, 424 53, 424 57, 424 7802, 424427, 424434, 424436, 424437, 424430, 424661, 424673, 424676, 424DIG15, 514944, 514945, 514966, 514967, 514968, A61K 900, A61K 3300
Patent
active
059355921
ABSTRACT:
A stable solution, cream, salve, or spray composition containing activated chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for the treatment of vaginitis and endometriosis by reducing any of Candida, Actinobacillus actinomycetemcomitans, Pseudomonades, and Porphyromonas gingivalis present in the vagina or the uterus. The preferred concentration ranges are in the range of about 0.005% to about 2.0% of chlorine dioxide, and in the range of about 0.02% to about 3.0% of phosphate. The phosphate compound retards escape of chlorine dioxide in the pH range of 6.0 to 7.4, at which pH chlorine dioxide becomes activated and releases sufficient chlorine dioxide to reduce motility and become lethal to the involved micro-organisms.
REFERENCES:
patent: 3271242 (1966-09-01), McNicholas
Anthony A. Rizzo, "The Possible Role of Hydrogen Sulfide in Human Periodontal Disease", Periodontics, vol. 5, No. 5, Sep./Oct. 1967, pp. 233, 235, 236.
Maria C. Solis-Gaffar, Thomas J. Fischer and Abdul Gaffar, "Instrumental Evaluation of Odor Produced by Specific Oral Microorganism", J. Soc. Cosmet. Chem., vol. 30, Jul./Aug. 1979, pp. 241-247.
W. NG and J. Tonzetich, "Effect of Hydrogen Sulfide and Methyl Mercaptan on the Permeability of Oral Mucosa", J. Dent. Res., vol. 6, No. 7, pp. 994-997, Jul. 1984.
I. Kleinberg and G. Westbay, "Salivary and Metabolic Factors Involved in Oral Malodor Formation", pp. 768-774, J. Periodontol, vol. 63, No. 9, Sep. 1992.
W.O. Engler, S.P. Ramfjord and J.J. Hiniker, "Development of Epithelial Attachment and Gingival Sulcus in Rhesus Monkeys", J. Periodontol, vol. 36, 1965, pp. 44-57.
R.J. Genco, T.E. Van Dyke, M.J. Levine, R.D. Nelson and M.E. Wilson, "Molecular Factors Influencing Defects in Periodontal Disease", 1985 Kreshover Lecture, J. Dent. Res., vol. 65, No. 12, Dec. 1986, pp. 1379-1380.
Federal Register, vol. 47, No. 101, Tuesday, May 25, 1982, "Proposed Rules", p. 22801.
J. Tonzetich, "Production and Orgin of Oral Malodor: A Review of Mechanisms and Methods of Analysis", J. Periodontol, vol. 48, No. 1, Jan. 1977, pp. 13-20.
Article entitled "Storage of Chlorine Dioxide", by W.J. Masschelein, Ann Arbor Science Publishers, Inc., 1979, pp. 138-140.
Bawa Raj
Micropure Inc.
LandOfFree
Method for treating vaginitis and endometriosis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for treating vaginitis and endometriosis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for treating vaginitis and endometriosis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1117682