Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector
Patent
1994-11-30
1999-08-10
Housel, James C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
424852, 4242751, 4242781, 530868, A61K 3935, A61K 3820
Patent
active
059355751
ABSTRACT:
This invention discloses a method for the treatment or prevention of autoimmune diseases, allergic or atopic disorders and graft rejection. Specifically, it provides a means of killing a specific sub-population of T lymphocytes while leaving the majority of other T lymphocytes in the population unaffected. The sub-population of T lymphocytes are killed by repeatedly challenging the population with an antigen in conjunction with administration of interleukin-4.
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Boehme Stefen A.
Critchfield Jeffrey
Lenardo Michael J.
Housel James C.
Krsek-Staples Julie
The United States of America as represented by the Department of
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