Piperazino derivatives as neurokinn antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514212, 514252, 540598, 540599, 544295, 544349, 544360, 544362, 544363, 544364, 544367, 544369, 544370, 544372, 544373, A61K 31495, C07D24104, C07D40112

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active

057958947

ABSTRACT:
The invention relates to compounds of the formula ##STR1## These compounds are neurokinin antagonists. These compounds are useful in the treatment of chronic airway diseases such as asthma.

REFERENCES:
patent: 5350852 (1994-09-01), Emonds-Alt et al.
patent: 5464788 (1995-11-01), Bock et al.
patent: 5719156 (1998-02-01), Shue et al.
Frossard et al, Life Sciences, vol. 49, pp. 1941-1953 (1991).

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