Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1997-02-04
1998-08-18
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 15, 435 21, C12Q 142, C12Q 148, C12Q 170
Patent
active
057957134
ABSTRACT:
Methods for identifying inducers and inhibitors of programmed cell death in a cell-free system are described. The methods exploit the finding that programmed cell death is accompanied by shutdown of cellular protein synthesis and by phosphorylation of eIF-2.alpha. and that the dephosphorylation of eIF-2.alpha. prevents the shutdown of protein synthesis.
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He Bin
Roizman Bernard
ARCH Development Corporation
Saunders David
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