Treating arteriosclerosis using benzimidazole compositions

Details Treating arteriosclerosis using benzimidazole compositions Treating arteriosclerosis using benzimidazole compositions

1993-07-21

1995-02-07

Henley, III, Raymond J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142358, 5142375, 5142378, 514387, 514394, 514392, 514398, 514400, 514396, A61K 31415, A61K 31535

Patent

active

053876008

ABSTRACT:
Disclosed are an antihyperlipidemia or antiarteriosclerosis agent comprising a certain benzimidazole or 2,2'-methylenebisphenol derivative such as 5-dodecanoylamino-2-mercaptobenzimidazole or 2,2'-isobutylidenebis(4,6-dimethyphenol).

REFERENCES:
patent: 3658822 (1972-04-01), Fauran et al.
patent: 4814329 (1989-03-01), Harsanyl et al.
American Journal of Pathology, vol. 139. No. 1, Jul. 1, 1991, pp. 217-229, McGuire et al, "Peroxisome Induction Potential and Lipid-Regulating Activity in Rats".
The Merck Index, 1989, Merck & Co., Rahway USA, p. 1156, No. 7245; 1462-3, No. 9217; and pp. 168-169, Nos. 1091, 1092.
International Journal of Obesity, vol. 11, 1987, pp. 619-629, F. M. Whittington et al, "Effect of Sodium 2-n-pentadecyl-benzimidazole-5-carboxylate . . . and lean mice".

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