Method for the preparation of 2-perfluoroalkyl-3-oxazolin-5-one

Details Method for the preparation of 2-perfluoroalkyl-3-oxazolin-5-one Method for the preparation of 2-perfluoroalkyl-3-oxazolin-5-one

1993-12-30

1997-08-19

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D26342

Patent

active

056590466

ABSTRACT:
There is provided a method for the preparation of a 2-perfluoroalkyl-3-oxazolin-5-one compound comprising reacting an aminonitrile with a perfluoroacylating agent in the presence of a solvent to form a perfluoroalkanoyl aminonitrile intermediate and cyclizing the intermediate in the presence of an acid and at least one molar equivalent of water.

REFERENCES:
patent: 5010098 (1991-04-01), Brown et al.
patent: 5028256 (1991-07-01), Martin
patent: 5030735 (1991-07-01), Addor et al.
patent: 5118816 (1992-06-01), Doehner, Jr. et al.
patent: 5426225 (1995-06-01), Kameswaran
patent: 5446170 (1995-08-01), Kameswaryn
patent: 5453508 (1995-09-01), Knapp
Martin, W.L.; Owens, D.A.; Comer, W.T.; Deitchman, D.; Ferguson, H.C. Seidehamel, R.J.; Young, J.R. Journal of Medicinal Chemistry, 1973, 16, 901.
Poupaert et al. Chem. Abstr. vol. 78 entry 43335 (1972).
Hawley "Condensed Chemical Dictionary" 10th Ed. Van Nostrand, N.Y., pp. 13-14, 11 (1981).

Affiliated with

Also associated with

Rating

Method for the preparation of 2-perfluoroalkyl-3-oxazolin-5-one does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for the preparation of 2-perfluoroalkyl-3-oxazolin-5-one, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the preparation of 2-perfluoroalkyl-3-oxazolin-5-one will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1105849