Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1997-08-19
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514252, 514717, 514736, 544358, 544359, 568639, 568647, 568655, 568774, 568775, 568807, A61K 31495, C07C 4320
Patent
active
056589140
ABSTRACT:
Diphenylcyclopropyl analogs in which one or more of the phenyl rings includes alkoxy substituents including a dialkylaminoalkoxy group, an unsubstituted piperazine alkoxy group, a substituted piperazine alkoxy group, an unsubstituted piperidine alkoxy group, and a substituted piperidine alkoxy group, and which may have one or two alkyl groups bonded to the cyclopropane. The compounds are useful as antiestrogens and anti-tumor agents.
REFERENCES:
patent: 4442119 (1984-04-01), Magarian et al.
patent: 4879315 (1989-11-01), Magarian et al.
patent: 5015666 (1991-05-01), Magarian et al.
patent: 5098903 (1992-03-01), Magarian et al.
patent: 5324736 (1994-06-01), Magarian et al.
patent: 5397802 (1995-03-01), Magarian et al.
patent: 5422367 (1995-06-01), Magarian et al.
Day et al., "Synthesis and Biological Evaluation of a Series of 1,1-Dichloro-2,2,3-triarylcyclopropanes as Pure Antiestrogens", Journal of Medicinal Chemistry, 1991, vol. 34, No. 2, pp. 842-851.
Magarian Robert A.
Overacre Lynette
Pento Joseph T.
Cintins Marianne M.
Jones Dwayne C.
Research Corporation Technologies
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