N-oxide prodrug derivatives of 3-hydroxy morphinans and partial

Details N-oxide prodrug derivatives of 3-hydroxy morphinans and partial N-oxide prodrug derivatives of 3-hydroxy morphinans and partial

1989-07-27

1991-02-05

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 46, 540477, C07D22126, C07D22128, C07D48708

Patent

active

049906178

ABSTRACT:
N-oxide prodrug derivatives of 3-hydroxy morphinan and partial morphinan analgesics, agonist-antogonists, and narcotic antagonists are useful therapeutic entities which provide enhanced bioavailability of 3-hydroxy morphinans and partial morphinans from orally administered dosage forms.

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