Pyrimidoindoles useful as hypoglycaemics

Details Pyrimidoindoles useful as hypoglycaemics Pyrimidoindoles useful as hypoglycaemics

1987-03-09

1988-11-15

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544252, A61K 31505, C07D48704

Patent

active

047849967

ABSTRACT:
Compounds of formula ##STR1## wherein A represents a lower alkylene chain optionally containing one double or triple bond, RO represents (lower)alkoxy, aryl(lower)alkoxy, hydroxy or protected hydroxy, R.sup.1 and R.sup.2 which may be the same or different each represent hydrogen, hydroxyl, lower alkyl, lower alkoxy, halo(lower)alkyl, halogen, amino or mono- or di(lower)alkylamino and R.sup.3 and R.sup.4 each independently represent hydrogen or lower alkyl and their pharmaceutically acceptable acid addition salts are useful as hypoglycaemics or as intermediates for hypoglycaemics.

REFERENCES:
patent: 2984666 (1961-05-01), Bortnick et al.
patent: 3634426 (1972-01-01), Eberle
patent: 3891644 (1975-06-01), White

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