Ointments containing FK-506 or derivatives thereof

Details Ointments containing FK-506 or derivatives thereof Ointments containing FK-506 or derivatives thereof

1993-05-17

1995-01-31

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514214, 514411, 514947, 514969, A61K 31445, A61K 3140

Patent

active

053859073

ABSTRACT:
An ointment comprising a tricyclic compound such as FK 506 substance which is 17-allyl-1,14-dihydroxy-12-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylviny l]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1 .0.sup.4,9 ]octacos-18-ene-2,3,10,16-tetraone, or the like, a solubilizing and/or absorption-promoting agent and an ointment base, which is useful for treating various skin diseases.

REFERENCES:
patent: 5061700 (1991-10-01), Dow et al.
Chemical Abstracts 111:89968c (1989).
Chemical Abstracts 112:91786f (1990).

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