Novel methods and compounds employed therein

Details Novel methods and compounds employed therein Novel methods and compounds employed therein

1973-11-19

1976-06-08

Shaver, Paul F.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260456A, 2603068D, 2602471P, 2602475E, 260268H, 26029354, C07C 9102, C07C 9302, C07C 9310, C07C 9502

Patent

active

039623386

ABSTRACT:
Preparation of an optically active alkamine in the sinister configuration, or a derivative of said alkamine, which is reacted with an 3-X-4-chloro(or RO-- where R is hydrogen or an alkali metal)-1,2,5-thiadiazole to prepare S-3-X-4-(3-substituted amino-2-hydroxypropoxy)-1,2,5-thiadiazole beta adrenergic blocking agents. Novel 3-morpholino-4-chloro(or RO--)-1,2,5-thiadiazoles and their preparation also are described.

REFERENCES:
patent: 2042621 (1936-06-01), Olin
patent: 2784233 (1957-03-01), Kottler et al.

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