Asialoganglioside related compounds

Details Asialoganglioside related compounds Asialoganglioside related compounds

1986-02-24

1991-02-05

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 172, 536123, C07H 506

Patent

active

049906046

ABSTRACT:
Method for the production of asialoganglioside related compounds of the formula (I). ##STR1## wherein R.sup.1 is hydrogen or benzoyl, R.sup.2 is hydrogen or acetyl, R.sup.3 is hydrogen, acetyl, .beta.-D-galactopyranosyl or 2,3,4,6-tetra-O-acetyl-.beta.-D-galactopyranosyl, R.sup.7 and R.sup.8 are individually alkyl having 1 to 30 carbon atoms and Ac is acetyl.

REFERENCES:
Migrdechian, Organic Synthesis, vol. 1, 1957; pages 39 and 429.
Sugimoto et al., Glycoconjugate J. (1985), vol. 2, pp. 11-15.
March, Advanced Organic Chemistry: Reactions Mechanisms and Structure, 1968, pp. 669.
The Merck Index, 9th ed., 1976, p. 562; No. 4201.
Young et al., Chemical Abstracts, vol. 92, No. 144763y (1980).
Urdal et al., Chemical Abstracts, vol. 93, No. 210472 (1980).
Wessel H-P, Iversen T, Bundle DR (1984) Carbohydr. Res. 130:5-21.
Sabesan S., Lemieux RU (1984) Can. J. Chem. 62:644-54.
Paulsen H., Paal M., Hadamczyk D., Steiger K-M (1984), Carbohydr. Res. 131:C1-C5.

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