Plasma carboxypeptidase

Details Plasma carboxypeptidase Plasma carboxypeptidase

1993-12-15

1994-11-15

Wax, Robert A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

4352402, 4352523, 4353201, C12N 1557, C12N 121, C12N 510, C12N 1563

Patent

active

053649346

ABSTRACT:
A novel polypeptide, designated plasma carboxypeptidase B (PCPB), has been purified from human plasma. It has been cloned from a human liver cDNA library using PCR amplification. Provided herein is nucleic acid encoding PCPB useful in diagnostics and in the recombinant preparation of PCPB. PCPB is used in the preparation and purification of antibodies thereto, in the purification of plasminogen, in the inhibition of plasminogen activation by t-PA in the presence of fibrinogen, and in diagnostic assays.

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