Ergot peptide alkaloid derivatives, processes for their preparat

Details Ergot peptide alkaloid derivatives, processes for their preparat Ergot peptide alkaloid derivatives, processes for their preparat

1980-07-14

1986-09-02

Rollins, Alton D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544346, 544349, 560 60, A61K 3148, C07D51902

Patent

active

046096574

ABSTRACT:
This invention provides compounds of ##STR1## wherein R.sub.1 is benzyl or benzyl substituted by hydroxy, chlorine, fluorine, amino, amido, (C.sub.2-5) alkanoylamino, (C.sub.1-4) alkyl, (C.sub.1-4) alkylamino, (C.sub.1-4) alkoxy, (C.sub.1-4) alkylamido, di[(C.sub.1-4) alkyl]amino, or di[(C.sub.1-4) alkyl]amino,
R.sub.2, R.sub.4 and R.sub.5 are each (C.sub.1-4) alkyl, and
R.sub.3 is (C.sub.2-4) alkyl
are prolactin secretion promoters.

REFERENCES:
patent: 3422110 (1969-01-01), Stadler et al.
patent: 3586683 (1971-06-01), Stadler et al.
patent: 3846433 (1974-11-01), Stadler et al.
patent: 4145549 (1979-03-01), Stadler

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