Substituted isocytosines having histamine H.sub.2 -antagonist ac

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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546303, 546344, 546334, 546301, 546341, 546339, 546345, 544310, 544370, 260302R, 546152, 548342, 548337, A61K 31505, C07D23936

Patent

active

041548345

ABSTRACT:
The compounds are substituted isocytosines which are histamine H.sub.2 -antagonists. Two specific compounds of the present inventon are 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(3-pyridylmethyl)-4-py rimidone and 2-[2-(3-bromo-2-pyridylmethylthio)ethylamino]-5-(4-pyridylmethyl)-4-pyrimi done.

REFERENCES:
burger et al., Medincinal Chemistry, 3rd Edition, 1970, pp. 1588-1589.

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