Nucleic acid encoding neurotrophic factor four (NT-4), vectors,

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 694, 4353201, 4352401, 4352402, 536 235, 536 2351, C12N 510, C12N 1518, C12N 1512

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053647696

ABSTRACT:
A novel polypeptide, designated neurotrophic factor-4 (NT-4), has been identified by PCR amplification of human genomic DNA. Provided herein is nucleic acid encoding NT-4 useful in diagnostics and in the recombinant preparation of NT-4. NT-4 is used in the treatment of nerve cells and in diagnostic assays.

REFERENCES:
patent: 4699875 (1987-10-01), Appel et al.
patent: 4997929 (1991-03-01), Collins et al.
Ibanez et al. "Structure-Function Studies of Nerve Growth Factor: Functional Importance of Highly Conserved Amino Acid Residues" EMBO 9(5) 1477-1483, May 1990.
Berkemeier et al., Neuron, 7:857-866 (1991).
Wion et al., FEBS, 203:82-86 (1986).
Leibrock et al., Nature, 341: 149-152 (1989).
Tiercy & Shooter, J. Cell Biol., 103(6Pt.1): 2367-2378 (1986).
Korsching & Thoenen, PNAS USA, 80:3513-3516 (1983).
Shelton & Reichadt, PNAS USA, 81: 7951-7955 (1984).
Levi-Montalcini & Hamburger, J. Exp. Zool., 116: 321-361 (1951).
Oppenheim et al., J. Comp. Neurol., 210: 174-189 (1982).
Johnson et al., Trends Neurosc., 9: 33-37 (1986).
Thoenen et al., Rev. Physiol. Biochem. Pharmacol., 109: 145-178.
Barde et al., ENBO J., 1(5): 549-553 (1982).
Barde, Neuron. 2: 1525-1534 (1989).
Hefti, J. Neurosc., 6(8): 2155-2162 (1986).
Lindsay et al., Dev. Biol., 112: 319-328 (1985).
Hohn et al., Nature, 344: 339-341 (1990).
Maisonpierre et al., Science, 247: 1446-1451 (1990).
Coughlin & Collins, Dev. Biol., 110: 392-401 (1985).
Rosenthal et al., Neuron, 4: 767-773 (1990).
Hallbook, et al., Neuron. 6:845-858 (1991).

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