Gradual release structures made from fiber spinning techniques

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424405, 424484, 426548, 71 6413, A61F 1300

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active

053646274

ABSTRACT:
A delivery system and a process for making the system is provided for the gradual release of an active agent. The system comprises an active agent and a wall material. The delivery system is formed by melt spinning a mixture of particles of active agent and wall material into a fiber. The fiber has a longitudinal dimension and a cross sectional dimension, the cross sectional dimension being no greater than about 1 mm. The fiber has an exterior surface. The particles of active agent are dispersed throughout the wall material such that the particles of active agent are gradually released from the fiber when the fiber is contacted with a solvent specific to the active agent.

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