Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1984-06-28
1985-04-02
Shippen, Michael L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
548228, 548496, 562445, 562446, 562561, 562567, 562574, 562575, C07C 5109
Patent
active
045089213
ABSTRACT:
A process for preparing .alpha.-alkyl amino acids by enantioretentive .alpha.-alkylation of .alpha.-amino acids is described. The products are bioactive compounds including some useful as therapeutic agents.
REFERENCES:
patent: 3422135 (1969-01-01), Yamada
patent: 4264771 (1981-04-01), Steglich
patent: 4339589 (1982-07-01), Steglich
Greenstein, "Chemistry of the Amino Acids," vol. 3, p. 2559-2579, (1961).
Amato Joseph S.
Karady Sandor
Weinstock Leonard M.
Merck & Co. , Inc.
Monaco Mario A.
Robertson Alice O.
Shippen Michael L.
Sudol Michael C.
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