Positive inotropic 3-nitro-5-substituted ester and thioester-1,4

Details Positive inotropic 3-nitro-5-substituted ester and thioester-1,4 Positive inotropic 3-nitro-5-substituted ester and thioester-1,4

1985-05-15

1987-02-24

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546310, 546271, 546272, 514338, 514339, C07D21190, C07D40112, C07D41304, A61K 31455

Patent

active

046457755

ABSTRACT:
Novel 3-nitro-dihydropyridine derivatives of the formula ##STR1## in which R.sub.1 and R.sub.2 each independently is hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.12 -alkoxy, C.sub.1 -C.sub.4 -halogenoalkoxy, halogen, nitro, C.sub.1 -C.sub.4 -halogenoalkyl, C.sub.1 -C.sub.4 -halogenoalkylmercapto, ##STR2## Z is oxygen or sulphur, R.sub.4 and R.sub.5 each independently is hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.6 -alkoxy, halogen, C.sub.1 -C.sub.4 -halogenoalkyl, C.sub.1 -C.sub.4 -halogenoalkoxy or nitro, or

REFERENCES:
patent: 4248873 (1981-02-01), Bossert et al.
patent: 4532248 (1985-07-01), Franckowiak et al.

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