2-phenyl-hexahydro-1,2,4-triazine-3,5-diones

Details 2-phenyl-hexahydro-1,2,4-triazine-3,5-diones 2-phenyl-hexahydro-1,2,4-triazine-3,5-diones

1985-03-08

1987-02-03

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514227, 514238, 514242, 544182, 544112, 544 60, 544 83, 544 586, C07D25306, A61K 3153, A61K 31535, A61K 3154

Patent

active

046409173

ABSTRACT:
Substituted 2-phenyl-hexahydro-1,2,4-triazine-3,5-diones of the formula ##STR1## in which n is one, two or three and the individual substituents R are independently of one another (a) hydrogen, fluorine, chlorine, bromine, iodine, trifluoromethyl, alkyl having 1 to 6 carbon atoms, cycloalkyl having 3 to 6 carbon atoms, alkoxy, alkylthio, alkylsulfinyl or alkylsulfonyl each having 1 to 6 carbon atoms in the alkyl moiety, nitro, cyano, amino, alkylamino or dialkylamino each having 1 to 12 carbon atoms in the alkyl moiety, piperidino, morpholino, thiomorpholino, 1-pyrrolidinyl, 4-methyl-1-piperazinyl or acylamino having 1 to 6 carbon atoms in the acyl moiety, or (b) a phenoxy, phenylthio, phenylsulfinyl, phenylsulfonyl, benzoyl, benzoylamino or aniline radical which is in each case R.sub.(a) -substituted, and the alkali metal salts, alkaline earth metal salts or ammonium salts thereof, a process for their preparation, their use, veterinary drugs and a process for controlling protozoal diseases.

REFERENCES:
patent: 3560496 (1971-02-01), Howes et al.
patent: 3655891 (1972-04-01), Howes et al.
patent: 3905971 (1975-09-01), Miller
patent: 3912723 (1975-10-01), Miller
patent: 4198407 (1980-04-01), Rosner et al.
patent: 4426522 (1984-01-01), Simonovitch
Chem. Abs., 92:51708u, Miller et al., I (1980).
Chem. Abs., 95:180,651f, Miller et al., II (1981).
Chem. Abs., 88:152,571s, Minlibaeva et al., (1978).

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